Online tools developed by MTi and/or RPBS members:

• MTiOpenScreen
  Virtual screening of drug-like diverse or “PPI” friendly compounds
  http://bioserv.rpbs.univ-paris-diderot.fr/services/MTiOpenScreen/

• FAF-Drugs3
  ADME-Tox prediction and filtering of drug-like or lead-like compounds; toxicophores and PAINS detection
  http://fafdrugs3.mti.univ-paris-diderot.fr

• Frog2
  Generation of multiple 3D structures of small organic molecules
  http://bioserv.rpbs.univ-paris-diderot.fr/services/Frog2/

• iPPI-DB
  Manually curated database of small inhibitors of protein-protein interactions( soon ~2K compounds)
  http://www.cdithem.fr/ippidb/v2

• SA-CONF
  Comparison of multiple conformations of a given target
  Download SA-CONF   SA-CONF Tutorial

• PCE
  Web tools to compute protein continuum electrostatics
  http://bioserv.rpbs.univ-paris-diderot.fr/services/PCE/

• PEP-FOLD
  An updated de novo structure prediction server for both linear and disulfide bonded cyclic peptides
  http://bioserv.rpbs.univ-paris-diderot.fr/PEP-FOLD

• PockDrug-Server
  A new web server for predicting pocket druggability on holo and apo proteins
  http://pockdrug.rpbs.univ-paris-diderot.fr

• Fpocket, hpocket, mdpocket
  Binding pocket predictions
  http://bioserv.rpbs.univ-paris-diderot.fr/services/fpocket/

• PEP-SiteFinder
  A tool for the blind identification of peptide binding sites on protein surfaces
  http://bioserv.rpbs.univ-paris-diderot.fr/PEP-SiteFinder

• ChemProt-2.0
  Visual navigation in a disease chemical biology database
  http://www.cbs.dtu.dk/services/ChemProt-2.0

• HExpoChem
  A systems biology resource to explore human exposure to chemicals
  http://www.cbs.dtu.dk/services/HExpoChem-1.0

• BCSearch
  Fast structural fragment mining over large collections of protein structures
  http://bioserv.rpbs.univ-paris-diderot.fr/services/BCSearch

• BactPepDB
  A database of predicted peptides from a exhaustive survey of complete prokaryote genomes
  http://www.yeastgenome.org

• MS-DOCK
  Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening (Sauton et al. BMC Bioinformatics. 2008, 9:184)
  http://dock.compbio.ucsf.edu/Contributed_Code/index.htm

• AMMOS
  This is a web-server tool to refine the 3D structures of compounds and of compounds docked into a protein target. (Pencheva T et al., BMC Bioinformatics. 2008, 9:438)
  http://mobyle.rpbs.univ-paris-diderot.fr/cgi-bin/portal.py#forms::rpbs.AMMOS

• DG-AMMOS
  A New tool to generate 3D conformation of small molecules using Distance Geometry and Automated Molecular Mechanics Optimization for in silico Screening. (Lagorce et al. BMC Chemical Biology 2009, 9:6)
  http://mobyle.rpbs.univ-paris-diderot.fr/cgi-bin/portal.py#forms::rpbs.DG-AMMOS